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A rationally engineered misacylating aminoacyl-tRNA synthetase

Information transfer from nucleic acid to protein is mediated by aminoacyl-tRNA synthetases, which catalyze the specific pairings of amino acids with transfer RNAs. Despite copious sequence and structural information on the 22 tRNA synthetase families, little is known of the enzyme signatures that s...

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Main Authors: Bullock, Timothy L., Rodríguez-Hernández, Annia, Corigliano, Eleonora M., Perona, John J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396676/
https://ncbi.nlm.nih.gov/pubmed/18477696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711812105
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