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Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion

Isoform A of phosphatidylinositol 3-kinase enhancer (PIKE-A) is a newly identified prooncogenic factor that has been implicated in cancer cell growth. How PIKE-A activity is regulated in response to growth signal is poorly understood. Here, we demonstrate that cyclin dependent kinase 5 (Cdk5), a pro...

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Hlavní autoři: Liu, Ren, Tian, Bo, Gearing, Marla, Hunter, Stephen, Ye, Keqiang, Mao, Zixu
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396674/
https://ncbi.nlm.nih.gov/pubmed/18487454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712306105
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