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Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion
Isoform A of phosphatidylinositol 3-kinase enhancer (PIKE-A) is a newly identified prooncogenic factor that has been implicated in cancer cell growth. How PIKE-A activity is regulated in response to growth signal is poorly understood. Here, we demonstrate that cyclin dependent kinase 5 (Cdk5), a pro...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396674/ https://ncbi.nlm.nih.gov/pubmed/18487454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712306105 |
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