Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

BACKGROUND: Ubiquitin (E3) ligases interact with specific ubiquitin conjugating (E2) enzymes to ubiquitinate particular substrate proteins. As the combination of E2 and E3 dictates the type and biological consequence of ubiquitination, it is important to understand the basis of specificity in E2:E3...

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Bibliographic Details
Main Authors: Xu, Zhen, Kohli, Ekta, Devlin, Karl I, Bold, Michael, Nix, Jay C, Misra, Saurav
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396629/
https://ncbi.nlm.nih.gov/pubmed/18485199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-26
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