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Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

The premature-ageing disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by constitutive production of progerin, a mutant form of the nuclear architectural protein lamin A1,2. Progerin is also expressed sporadically in wild-type cells and has been linked to physiological ageing3. Cells fro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Scaffidi, Paola, Misteli, Tom
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396576/
https://ncbi.nlm.nih.gov/pubmed/18311132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1708
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