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Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins

Aberrant proteins represent an extreme hazard to cells. Therefore, molecular chaperones and proteases have to carry out protein quality control in each cellular compartment. In contrast to the ATP-dependent cytosolic proteases and chaperones, the molecular mechanisms of extracytosolic factors are la...

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Autores principales: Krojer, Tobias, Pangerl, Karen, Kurt, Juliane, Sawa, Justyna, Stingl, Christoph, Mechtler, Karl, Huber, Robert, Ehrmann, Michael, Clausen, Tim
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396557/
https://ncbi.nlm.nih.gov/pubmed/18505836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803392105
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