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Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins

Aberrant proteins represent an extreme hazard to cells. Therefore, molecular chaperones and proteases have to carry out protein quality control in each cellular compartment. In contrast to the ATP-dependent cytosolic proteases and chaperones, the molecular mechanisms of extracytosolic factors are la...

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Detalhes bibliográficos
Main Authors: Krojer, Tobias, Pangerl, Karen, Kurt, Juliane, Sawa, Justyna, Stingl, Christoph, Mechtler, Karl, Huber, Robert, Ehrmann, Michael, Clausen, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396557/
https://ncbi.nlm.nih.gov/pubmed/18505836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803392105
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