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Estrogen and Aging Affect Synaptic Distribution of Phosphorylated LIM Kinase (LIMK) in CA1 Region of Female Rat Hippocampus
17β-Estradiol (E) increases axospinous synapse density in the hippocampal CA1 region of young female rats, but not in aged rats. This may be linked to age-related alterations in signaling pathways activated by synaptic estrogen receptor α (ER-α) that potentially regulate spine formation, such as LIM...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396523/ https://ncbi.nlm.nih.gov/pubmed/18294775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.01.004 |
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