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ESTROGEN AND AGING AFFECT THE SYNAPTIC DISTRIBUTION OF ESTROGEN RECEPTOR BETA-IMMUNOREACTIVITY IN THE CA1 REGION OF FEMALE RAT HIPPOCAMPUS

Estradiol (E) mediates increased synaptogenesis in the hippocampal CA1 stratum radiatum (sr) and enhances memory in young and some aged female rats, depending on dose and age. Young females rats express more estrogen receptor α (ERα) immunolabeling in CA1sr spine synapse complexes than aged rats and...

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Bibliographic Details
Main Authors: Waters, Elizabeth M., Yildirim, Murat, Janssen, William G.M., Lou, W.Y. Wendy, McEwen, Bruce S., Morrison, John H., Milner, Teresa A.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046233/
https://ncbi.nlm.nih.gov/pubmed/20875808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.09.069
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