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Inhibition of p38 MAPK Suppresses Inflammatory Cytokine Induction by Etoposide, 5-Fluorouracil, and Doxorubicin without Affecting Tumoricidal Activity
Cancer patients undergoing treatment with systemic cancer chemotherapy drugs often experience debilitating fatigue similar to sickness behavior, a normal response to infection or tissue damage caused by the production of the inflammatory cytokines IL-1β, TNF-α, and IL-6. The p38 mitogen activated pr...
Gorde:
Egile Nagusiak: | , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Public Library of Science
2008
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396285/ https://ncbi.nlm.nih.gov/pubmed/18523641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002355 |
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