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Abrogation of Anti-Inflammatory Transcription Factor LKLF in Neutrophil-Dominated Airways

This is the first report to describe a role for Lung Kruppel-like Factor (LKLF or KLF2) in inflammatory airways diseases. In the present study, we identify that LKLF is constitutively expressed in the small airways of normal lungs; however, its expression disappears in severe airway diseases, such a...

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Detalhes bibliográficos
Main Authors: Saavedra, Milene T., Patterson, Abby D., West, James, Randell, Scott H., Riches, David W., Malcolm, Ken C., Cool, Carlyne D., Nick, Jerry A., Dinarello, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396247/
https://ncbi.nlm.nih.gov/pubmed/18218994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0282OC
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