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Comparative Neuropathogenesis and Neurovirulence of Attenuated Flaviviruses in Nonhuman Primates
Based on previous preclinical evaluation in mice and monkeys, the chimeric TBEV/DEN4Δ30 virus, carrying the prM and E protein genes from a highly virulent Far Eastern strain of tick-borne encephalitis virus (TBEV) on the backbone of a nonneuroinvasive dengue type 4 virus (DEN4), has been identified...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395187/ https://ncbi.nlm.nih.gov/pubmed/18353947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00172-08 |
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