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Herpes Simplex Virus Virion Host Shutoff Attenuates Establishment of the Antiviral State
Herpes simplex virus mutants lacking the vhs protein are severely attenuated in animal models of pathogenesis and exhibit reduced growth in primary cell culture. As a result of these properties, viruses with vhs deleted have been proposed as live-attenuated vaccines. Despite these findings and their...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395185/ https://ncbi.nlm.nih.gov/pubmed/18367525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02047-07 |
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