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Herpes Simplex Virus Virion Host Shutoff Attenuates Establishment of the Antiviral State
Herpes simplex virus mutants lacking the vhs protein are severely attenuated in animal models of pathogenesis and exhibit reduced growth in primary cell culture. As a result of these properties, viruses with vhs deleted have been proposed as live-attenuated vaccines. Despite these findings and their...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395185/ https://ncbi.nlm.nih.gov/pubmed/18367525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02047-07 |
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