Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid

Control of human immunodeficiency virus type 1 (HIV-1) by HLA-B27-positive subjects has been linked to an immunodominant CD8(+) cytotoxic T-lymphocyte (CTL) response targeting the conserved KK10 epitope (KRWIILGLNK(263-272)) in p24/Gag. Viral escape in KK10 typically occurs through development of an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schneidewind, Arne, Brockman, Mark A., Sidney, John, Wang, Yaoyu E., Chen, Huabiao, Suscovich, Todd J., Li, Bin, Adam, Rahma I., Allgaier, Rachel L., Mothé, Bianca R., Kuntzen, Thomas, Oniangue-Ndza, Cesar, Trocha, Alicja, Yu, Xu G., Brander, Christian, Sette, Alessandro, Walker, Bruce D., Allen, Todd M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Pathogenesis and Immunity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395179/
https://ncbi.nlm.nih.gov/pubmed/18385228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02356-07
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