Subdominant CD8 T-Cell Epitopes Account for Protection against Cytomegalovirus Independent of Immunodomination

Cytomegalovirus (CMV) infection continues to be a complication in recipients of hematopoietic stem cell transplantation (HSCT). Preexisting donor immunity is recognized as a favorable prognostic factor for the reconstitution of protective antiviral immunity mediated primarily by CD8 T cells. Further...

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Autori principali: Holtappels, Rafaela, Simon, Christian O., Munks, Michael W., Thomas, Doris, Deegen, Petra, Kühnapfel, Birgit, Däubner, Torsten, Emde, Simone F., Podlech, Jürgen, Grzimek, Natascha K. A., Oehrlein-Karpi, Silke A., Hill, Ann B., Reddehase, Matthias J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395166/
https://ncbi.nlm.nih.gov/pubmed/18367531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00155-08
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