Increased thrombin responsiveness in platelets from mice lacking glycoprotein V

A role for glycoprotein (GP)V in platelet function has been proposed on the basis of observations that GP V is the major thrombin substrate on intact platelets cleaved during thrombin-induced platelet aggregation, and that GP V promotes GP Ib-IX surface expression in heterologous cells. We tested th...

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Autors principals: Ramakrishnan, Vanitha, Reeves, Peter S., DeGuzman, Francis, Deshpande, Usha, Ministri-Madrid, Kathleen, DuBridge, Robert B., Phillips, David R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23948/
https://ncbi.nlm.nih.gov/pubmed/10557321
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