Evolutionary history and functional implications of protein domains and their combinations in eukaryotes

BACKGROUND: In higher multicellular eukaryotes, complex protein domain combinations contribute to various cellular functions such as regulation of intercellular or intracellular signaling and interactions. To elucidate the characteristics and evolutionary mechanisms that underlie such domain combina...

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Detalhes bibliográficos
Main Authors: Itoh, Masumi, Nacher, Jose C, Kuma, Kei-ichi, Goto, Susumu, Kanehisa, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394772/
https://ncbi.nlm.nih.gov/pubmed/17588271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-6-r121
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