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Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design

Many cellular functions in eukaryotic pathogens are mediated by the cyclic nucleotide binding (CNB) domain, which senses second messengers such as cyclic AMP and cyclic GMP. Although CNB domain-containing proteins have been identified in many pathogenic organisms, an incomplete understanding of how...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Mohanty, Smita, Kennedy, Eileen J., Herberg, Friedrich W., Hui, Raymond, Taylor, Susan S., Langsley, Gordon, Kannan, Natarajan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577300/
https://ncbi.nlm.nih.gov/pubmed/25847873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.03.012
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