Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design

Many cellular functions in eukaryotic pathogens are mediated by the cyclic nucleotide binding (CNB) domain, which senses second messengers such as cyclic AMP and cyclic GMP. Although CNB domain-containing proteins have been identified in many pathogenic organisms, an incomplete understanding of how...

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Publicado en:Biochim Biophys Acta
Main Authors: Mohanty, Smita, Kennedy, Eileen J., Herberg, Friedrich W., Hui, Raymond, Taylor, Susan S., Langsley, Gordon, Kannan, Natarajan
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577300/
https://ncbi.nlm.nih.gov/pubmed/25847873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.03.012
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