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Curcumin inhibits bTREK-1 K(+) channels and stimulates cortisol secretion from adrenocortical cells

Bovine adrenal zona fasciculata (AZF) cells express bTREK-1 K(+) channels that set the resting membrane potential. Inhibition of these channels by adrenocorticotropic hormone (ACTH) is coupled to membrane depolarization and cortisol secretion. Curcumin, a phytochemical with medicinal properties extr...

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Bibliografiske detaljer
Main Authors: Enyeart, Judith A., Liu, Haiyan, Enyeart, John J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394713/
https://ncbi.nlm.nih.gov/pubmed/18406348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.001
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