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Curcumin inhibits bTREK-1 K(+) channels and stimulates cortisol secretion from adrenocortical cells
Bovine adrenal zona fasciculata (AZF) cells express bTREK-1 K(+) channels that set the resting membrane potential. Inhibition of these channels by adrenocorticotropic hormone (ACTH) is coupled to membrane depolarization and cortisol secretion. Curcumin, a phytochemical with medicinal properties extr...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394713/ https://ncbi.nlm.nih.gov/pubmed/18406348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.001 |
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