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CHEK2 variants associate with hereditary prostate cancer
Recently, variants in CHEK2 gene were shown to associate with sporadic prostate cancer in the USA. In the present study from Finland, we found that the frequency of 1100delC, a truncating variant that abrogates the kinase activity, was significantly elevated among 120 patients with hereditary prosta...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394451/ https://ncbi.nlm.nih.gov/pubmed/14612911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601425 |
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