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p16 gene transfer increases cell killing with abnormal nucleation after ionising radiation in glioma cells
It is well established that cells synchronised at the G1–S phase are highly radiosensitive. In this study, p16-null human glioma cell lines were induced into G1 cell cycle arrest by adenovirus-mediated p16 gene transfer, and examined for radiation-induced cell killing. Clonogenic analysis and trypan...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394396/ https://ncbi.nlm.nih.gov/pubmed/14583787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601299 |
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