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Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells

Malignant gliomas highly coexpress platelet-derived growth factor (PDGF) and its receptor, suggesting the presence of an autocrine loop. Therefore, disruption of PDGF ligand/receptor complex represents a promising strategy for the treatment of malignant gliomas. However, the mechanisms of the antitu...

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Detalhes bibliográficos
Main Authors: Takeuchi, H, Kanzawa, T, Kondo, Y, Kondo, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409632/
https://ncbi.nlm.nih.gov/pubmed/14997209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601605
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