O(6)-methylguanine-DNA-methyltransferase expression and gene polymorphisms in relation to chemotherapeutic response in metastatic melanoma

In a retrospective study, O(6)-methylguanine-DNA-methyltransferase (MGMT) expression was analysed by immunohistochemistry using monoclonal human anti-MGMT antibody in melanoma metastases in patients receiving dacarbazine (DTIC) as single-drug therapy or as part of combination chemotherapy with DTIC–...

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Detalhes bibliográficos
Main Authors: Ma, S, Egyházi, S, Ueno, T, Lindholm, C, Kreklau, E L, Stierner, U, Ringborg, U, Hansson, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394337/
https://ncbi.nlm.nih.gov/pubmed/14562026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601270
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