Photodynamic therapy effect of m-THPC (Foscan®) in vivo: correlation with pharmacokinetics

m-Tetra(hydroxyphenyl)chlorin (m-THPC, Foscan, Temoporfin) has an unusually high photodynamic efficacy which cannot be explained by its photochemical properties alone. In vivo interactions are therefore of critical importance in determining this high potency. The pharmacokinetics of m-THPC in a rat...

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Bibliographic Details
Main Authors: Jones, H J, Vernon, D I, Brown, S B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394256/
https://ncbi.nlm.nih.gov/pubmed/12865935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601101
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