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Photodynamic therapy effect of m-THPC (Foscan®) in vivo: correlation with pharmacokinetics

m-Tetra(hydroxyphenyl)chlorin (m-THPC, Foscan, Temoporfin) has an unusually high photodynamic efficacy which cannot be explained by its photochemical properties alone. In vivo interactions are therefore of critical importance in determining this high potency. The pharmacokinetics of m-THPC in a rat...

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Detalhes bibliográficos
Main Authors: Jones, H J, Vernon, D I, Brown, S B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394256/
https://ncbi.nlm.nih.gov/pubmed/12865935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601101
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