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PPARδ regulates multiple proinflammatory pathways to suppress atherosclerosis
Lipid homeostasis and inflammation are key determinants in atherogenesis, exemplified by the requirement of lipid-laden, foam cell macrophages for atherosclerotic lesion formation. Although the nuclear receptor PPARδ has been implicated in both systemic lipid metabolism and macrophage inflammation,...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393796/ https://ncbi.nlm.nih.gov/pubmed/18337509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711875105 |
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