PPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

Activation of the nuclear hormone receptor peroxisome proliferator-activated receptor δ (PPARδ) has been shown to improve insulin resistance, adiposity, and plasma HDL levels. However, its antiatherogenic role remains controversial. Here we report atheroprotective effects of PPARδ activation in a mo...

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Autors principals: Takata, Yasunori, Liu, Joey, Yin, Fen, Collins, Alan R., Lyon, Christopher J., Lee, Chih-Hao, Atkins, Annette R., Downes, Michael, Barish, Grant D., Evans, Ronald M., Hsueh, Willa A., Tangirala, Rajendra K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393800/
https://ncbi.nlm.nih.gov/pubmed/18337495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708647105
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