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The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification
This study provides comprehensive characterization of the mode of action of bistramide A and identifies structural requirements of bistramide-based compounds that are responsible for severing actin filaments and inhibiting growth of cancer cells in vitro and in vivo. We rationally designed and assem...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393769/ https://ncbi.nlm.nih.gov/pubmed/18334642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710727105 |
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