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Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation
The protective antigen (PA) moiety of anthrax toxin forms a heptameric pore in endosomal membranes of mammalian cells and translocates the enzymatic moieties of the toxin to the cytosol of these cells. Phenylalanine-427 (F427), a solvent-exposed residue in the lumen of the pore, was identified earli...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393744/ https://ncbi.nlm.nih.gov/pubmed/18334631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800701105 |
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