Role of CypA and Hsp90 in membrane translocation mediated by anthrax Protective Antigen

Bacillus anthracis Lethal Toxin consists of the Protective Antigen (PA) and the metalloprotease Lethal Factor (LF). During cellular uptake PA forms pores in membranes of endosomes, and unfolded LF translocates through the pores into the cytosol. We have investigated whether host-cell chaperones faci...

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Hlavní autoři: Dmochewitz, Lydia, Lillich, Maren, Kaiser, Eva, Jennings, Laura D., Lang, Alexander E., Buchner, Johannes, Fischer, Gunter, Aktories, Klaus, Collier, R. John, Barth, Holger
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031994/
https://ncbi.nlm.nih.gov/pubmed/20946244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01539.x
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