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The discovery of new coding alleles of human CYP26A1 which are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system
Retinoic acid (RA) is a critical regulator of gene expression during embryonic development and in the maintenance of adult epithelial tissues. Genetic polymorphisms of CYP26A1 could cause inter-individual variation in the metabolism of retinoic acid, thus altering signaling during embryonic developm...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393551/ https://ncbi.nlm.nih.gov/pubmed/17460545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32801152d6 |
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