Evaluation of vaccines designed to induce protective cellular immunity against the Plasmodium yoelii circumsporozoite protein: vaccinia, pseudorabies, and Salmonella transformed with circumsporozoite gene.

In an attempt to induce a protective cytotoxic T-cell mediated immunity against sporozoites of Plasmodium yoelii, the gene encoding the P. yoelii circumsporozoite (CS) protein was engineered into three live vectors: vaccinia, attenuated pseudorabies, and attenuated Salmonella typhimurium. Balb/c mic...

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Main Authors: Sedegah, M., Beaudoin, R. L., Majarian, W. R., Cochran, M. D., Chiang, C. H., Sadoff, J., Aggarwal, A., Charoenvit, Y., Hoffman, S. L.
Formato: Artigo
Idioma:Inglês
Publicado em: World Health Organization 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393047/
https://ncbi.nlm.nih.gov/pubmed/2094576
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