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Monoclonal antibodies of three different immunoglobulin G isotypes produced by immunization with a synthetic peptide or native protein protect mice against challenge with Plasmodium yoelii sporozoites.

Passive transfer of monoclonal antibodies (MAbs) against malaria circumsporozoite (CS) proteins protects animals against malaria. Active immunization with synthetic or recombinant peptides induces a level of polyclonal antibodies to sporozoites comparable to those found after passive immunization bu...

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Bibliografiske detaljer
Main Authors: Ak, M, Bower, J H, Hoffman, S L, Sedegah, M, Lees, A, Carter, M, Beaudoin, R L, Charoenvit, Y
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC280874/
https://ncbi.nlm.nih.gov/pubmed/8500885
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