Human Antibodies against Plasmodium falciparum Liver-Stage Antigen 3 Cross-React with Plasmodium yoelii Preerythrocytic-Stage Epitopes and Inhibit Sporozoite Invasion In Vitro and In Vivo

The Plasmodium falciparum liver-stage antigen 3 (LSA3), a recently identified preerythrocytic antigen, induces protection against malaria in chimpanzees. Using antibodies from individuals with hyperimmunity to malaria affinity purified on recombinant or synthetic polypeptides of LSA3, we identified...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brahimi, Karima, Badell, Edgar, Sauzet, Jean-Pierre, BenMohamed, Lbachir, Daubersies, Pierre, Guérin-Marchand, Claudine, Snounou, George, Druilhe, Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98406/
https://ncbi.nlm.nih.gov/pubmed/11349050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.3845-3852.2001
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