Human Antibodies against Plasmodium falciparum Liver-Stage Antigen 3 Cross-React with Plasmodium yoelii Preerythrocytic-Stage Epitopes and Inhibit Sporozoite Invasion In Vitro and In Vivo

The Plasmodium falciparum liver-stage antigen 3 (LSA3), a recently identified preerythrocytic antigen, induces protection against malaria in chimpanzees. Using antibodies from individuals with hyperimmunity to malaria affinity purified on recombinant or synthetic polypeptides of LSA3, we identified...

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Autori principali: Brahimi, Karima, Badell, Edgar, Sauzet, Jean-Pierre, BenMohamed, Lbachir, Daubersies, Pierre, Guérin-Marchand, Claudine, Snounou, George, Druilhe, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98406/
https://ncbi.nlm.nih.gov/pubmed/11349050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.3845-3852.2001
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