Active and passive immunization against Plasmodium yoelii sporozoites.

Three subunit vaccines based on the major repeat, (QGPGAP)n, and flanking regions of the Plasmodium yoelii circumsporozoite protein were designed, produced, and tested. All were immunogenic, but none gave consistent protection against a 40-200 sporozoite challenge. To demonstrate that antibodies to...

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Autores principales: Charoenvit, Y., Sedegah, M., Yuan, L. F., Gross, M., Cole, C., Bechara, R., Leef, M. F., Robey, F. A., Lowell, G. H., Beaudoin, R. L.
Formato: Artigo
Lenguaje:Inglês
Publicado: World Health Organization 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393042/
https://ncbi.nlm.nih.gov/pubmed/1709834
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