Active and passive immunization against Plasmodium yoelii sporozoites.

Three subunit vaccines based on the major repeat, (QGPGAP)n, and flanking regions of the Plasmodium yoelii circumsporozoite protein were designed, produced, and tested. All were immunogenic, but none gave consistent protection against a 40-200 sporozoite challenge. To demonstrate that antibodies to...

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Autors principals: Charoenvit, Y., Sedegah, M., Yuan, L. F., Gross, M., Cole, C., Bechara, R., Leef, M. F., Robey, F. A., Lowell, G. H., Beaudoin, R. L.
Format: Artigo
Idioma:Inglês
Publicat: World Health Organization 1990
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393042/
https://ncbi.nlm.nih.gov/pubmed/1709834
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