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Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1
The tandem BRCA1 C-terminal (BRCT) domains are phospho-serine/threonine recognition modules essential for the function of BRCA1. Recent studies suggest that acetyl-CoA carboxylase 1 (ACC1), an enzyme with crucial roles in de novo fatty acid biosynthesis and lipogenesis and essential for cancer cell...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2392887/ https://ncbi.nlm.nih.gov/pubmed/18452305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800314m |
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