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A Continuum Method for Determining Membrane Protein Insertion Energies and the Problem of Charged Residues

Continuum electrostatic approaches have been extremely successful at describing the charged nature of soluble proteins and how they interact with binding partners. However, it is unclear whether continuum methods can be used to quantitatively understand the energetics of membrane protein insertion a...

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Detalhes bibliográficos
Main Authors: Choe, Seungho, Hecht, Karen A., Grabe, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391250/
https://ncbi.nlm.nih.gov/pubmed/18474636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200809959
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