Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia

BACKGROUND: Honeybee's sting on human skin can induce ongoing pain, hyperalgesia and inflammation. Injection of bee venom (BV) into the intraplantar surface of the rat hindpaw induces an early onset of spontaneous pain followed by a lasting thermal and mechanical hypersensitivity in the affecte...

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Detalhes bibliográficos
Main Authors: Cui, Xiu-Yu, Dai, Yi, Wang, Sheng-Lan, Yamanaka, Hiroki, Kobayashi, Kimiko, Obata, Koichi, Chen, Jun, Noguchi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391153/
https://ncbi.nlm.nih.gov/pubmed/18445299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-17
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