TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

Cold hyperalgesia is a well-documented symptom of inflammatory and neuropathic pain; however, the underlying mechanisms of this enhanced sensitivity to cold are poorly understood. A subset of transient receptor potential (TRP) channels mediates thermosensation and is expressed in sensory tissues, su...

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Detalhes bibliográficos
Main Authors: Obata, Koichi, Katsura, Hirokazu, Mizushima, Toshiyuki, Yamanaka, Hiroki, Kobayashi, Kimiko, Dai, Yi, Fukuoka, Tetsuo, Tokunaga, Atsushi, Tominaga, Makoto, Noguchi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187934/
https://ncbi.nlm.nih.gov/pubmed/16110328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25437
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