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Regulation of Aβ pathology by beclin 1: a protective role for autophagy?

The amyloid β (Aβ) peptide is thought to be a major culprit in Alzheimer disease (AD), and its production and degradation have been intensely investigated. Nevertheless, it remains largely unknown how Aβ pathology is modulated by the autophagy pathway. The study by Pickford and colleagues in this is...

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Detalhes bibliográficos
Main Authors: Lee, Jin-A, Gao, Fen-Biao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391068/
https://ncbi.nlm.nih.gov/pubmed/18497881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35662
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