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Regulation of Aβ pathology by beclin 1: a protective role for autophagy?
The amyloid β (Aβ) peptide is thought to be a major culprit in Alzheimer disease (AD), and its production and degradation have been intensely investigated. Nevertheless, it remains largely unknown how Aβ pathology is modulated by the autophagy pathway. The study by Pickford and colleagues in this is...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391068/ https://ncbi.nlm.nih.gov/pubmed/18497881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35662 |
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