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Regulation of Aβ pathology by beclin 1: a protective role for autophagy?

The amyloid β (Aβ) peptide is thought to be a major culprit in Alzheimer disease (AD), and its production and degradation have been intensely investigated. Nevertheless, it remains largely unknown how Aβ pathology is modulated by the autophagy pathway. The study by Pickford and colleagues in this is...

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Bibliografische gegevens
Hoofdauteurs: Lee, Jin-A, Gao, Fen-Biao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391068/
https://ncbi.nlm.nih.gov/pubmed/18497881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35662
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