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Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2

Nek8 is a serine/threonine kinase that is mutated in the jck (juvenile cystic kidneys) mouse, a model of autosomal recessive juvenile polycystic kidney disease, but its function is poorly understood. We used the jck mouse to study the functional relationship between Nek8 and other proteins that have...

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Sonraí Bibleagrafaíochta
Main Authors: Sohara, Eisei, Luo, Ying, Zhang, Jingjing, Manning, Danielle K., Beier, David R., Zhou, Jing
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391053/
https://ncbi.nlm.nih.gov/pubmed/18235101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006090985
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