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Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2

Nek8 is a serine/threonine kinase that is mutated in the jck (juvenile cystic kidneys) mouse, a model of autosomal recessive juvenile polycystic kidney disease, but its function is poorly understood. We used the jck mouse to study the functional relationship between Nek8 and other proteins that have...

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Main Authors: Sohara, Eisei, Luo, Ying, Zhang, Jingjing, Manning, Danielle K., Beier, David R., Zhou, Jing
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391053/
https://ncbi.nlm.nih.gov/pubmed/18235101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006090985
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