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Loss of the Ciliary Kinase Nek8 Causes Left-Right Asymmetry Defects
A missense mutation in mouse Nek8, which encodes a ciliary kinase, produces the juvenile cystic kidneys (jck) model of polycystic kidney disease, but the functions of Nek8 are incompletely understood. Here, we generated a Nek8-null allele and found that homozygous mutant mice die at birth and exhibi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537214/ https://ncbi.nlm.nih.gov/pubmed/23274954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050490 |
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