DHEA Induces 11β-HSD2 by Acting on CCAAT/Enhancer-Binding Proteins

11β-Hydroxysteroid dehydrogenase (11β-HSD) type 1 and type 2 catalyze the interconversion of inactive and active glucocorticoids. Impaired regulation of these enzymes has been associated with obesity, diabetes, hypertension, and cardiovascular disease. Previous studies in animals and humans suggeste...

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Bibliographic Details
Main Authors: Balazs, Zoltan, Schweizer, Roberto A.S., Frey, Felix J., Rohner-Jeanrenaud, Françoise, Odermatt, Alex
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2008
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391033/
https://ncbi.nlm.nih.gov/pubmed/18032797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030263
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