Hexose-6-phosphate Dehydrogenase Modulates 11β-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7β-hydroxy-neurosteroids

BACKGROUND: The role of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in the regulation of energy metabolism and immune system by locally reactivating glucocorticoids has been extensively studied. Experiments determining initial rates of enzyme activity revealed that 11β-HSD1 can catalyze both...

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Detalhes bibliográficos
Main Authors: Nashev, Lyubomir G., Chandsawangbhuwana, Charlie, Balazs, Zoltan, Atanasov, Atanas G., Dick, Bernhard, Frey, Felix J., Baker, Michael E., Odermatt, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891437/
https://ncbi.nlm.nih.gov/pubmed/17593962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000561
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