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Mucosal Immunization With Salmonella typhimurium Expressing Lassa Virus Nucleocapsid Protein Cross-protects Mice From Lethal Challenge With Lymphocytic Choriomeningitis Virus
OBJECTIVES: Lassa fever virus (LAS) is transmitted to man by rodent carriers and is fatal in a third of untreated cases. Our goal is to provide immune protection from Lassa fever by mucosal vaccination. STUDY DESIGN/METHODS: Mice were vaccinated intragastrically with control vectors or with vectors...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391007/ https://ncbi.nlm.nih.gov/pubmed/11437313 |
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