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Mucosal Immunization With Salmonella typhimurium Expressing Lassa Virus Nucleocapsid Protein Cross-protects Mice From Lethal Challenge With Lymphocytic Choriomeningitis Virus

OBJECTIVES: Lassa fever virus (LAS) is transmitted to man by rodent carriers and is fatal in a third of untreated cases. Our goal is to provide immune protection from Lassa fever by mucosal vaccination. STUDY DESIGN/METHODS: Mice were vaccinated intragastrically with control vectors or with vectors...

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Detalhes bibliográficos
Main Authors: Djavani, Mahmoud, Yin, Cheng, Lukashevich, Igor S., Rodas, Juan, Rai, Sharath K., Salvato, Maria S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391007/
https://ncbi.nlm.nih.gov/pubmed/11437313
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